Article

FKN regulates macrophage activation in lupus nephritis via the Hippo signaling pathway

2022-08-03

Abstract excerpt

<h4>Introduction: </h4> Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE), and its pathogenesis is not fully understood. There is an imbalance in the polarization of macrophages and an interplay between fractalkine (FKN) and its receptor, CX3CR1, in LN. Previously we showed that the expression levels of FKN were positively correlated with the severity of LN. Here we aimed to stud...

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Literature Corpus work: ca3e0ce1-f7dd-5b41-a9d7-c0785db8a61d
DOI: 10.21203/rs.3.rs-1722971/v1

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