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Article

Transcriptional expression of CXCL10 and STAT1 in lupus nephritis and the intervention effect of triptolide

14 Nov 2022

Abstract excerpt

OBJECTIVE: This study screened out the key genes associated with the occurrence and development of lupus nephritis (LN) using bioinformatics methods, and then explored the expression of key genes in LN and the inhibitory effect of triptolide. METHODS: The GEO2R online tool in the GEO database was used to perform differential analysis of gene expression in LN tissues and normal kidney tissues. The GO function and...

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PMID: 36374433
DOI: 10.1007/s10067-022-06400-y

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