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Article

Endothelial Cell-Specific Molecule-1 Inhibits Albuminuria in Diabetic Mice

2021-10-15

Abstract excerpt

Diabetic kidney disease (DKD) is the most common cause of kidney failure in the world, and novel predictive biomarkers and molecular mechanisms of disease are needed. Endothelial cell-specific molecule-1 (Esm-1) is a secreted proteoglycan that attenuates inflammation. We previously identified that a glomerular deficiency of Esm-1 associates with more pronounced albuminuria and glomerular inflammation in DKD-suscep...

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Literature Corpus work
ca356c4c-8781-58ba-b6f7-fb55910c8a5d
DOI
10.1101/2021.10.14.464296
Open publication

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Endothelial Cell-Specific Molecule-1 Inhibits Albuminuria in Diabetic MiceDOI 10.1101/2021.10.14.464296
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