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Article

Comprehensive Search for Novel Circulating miRNAs and Axon Guidance Pathway Proteins Associated with Risk of ESKD in Diabetes

17 Jun 2021

Abstract excerpt

Significance Statement Mechanisms underlying the progression of diabetic kidney disease to ESKD are not fully understood. Through profiling of circulating microRNAs (miRNAs) and proteins in individuals with type 1 and type 2 diabetes from four independent cohorts, the authors identified a signature of 17 miRNAs and six axon guidance pathway proteins that were robustly associated with severity of early structural...

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PMID: 34140396
DOI: 10.1681/asn.2021010105

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