Article

Esm-1 mediates transcriptional polarization associated with diabetic kidney disease

2023-03-02

Abstract excerpt

<h4>Background</h4> Esm-1, endothelial cell-specific molecule-1, is a susceptibility gene for diabetic kidney disease (DKD) and is a cytokine- and glucose-regulated, secreted proteoglycan, that is notably expressed in kidney and attenuates inflammation and albuminuria. Esm1 has restricted expression at the vascular tip during development but little is known about its expression pattern in mature tissues, and its...

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Literature Corpus work: 1460b9e1-c39a-5643-9fea-a28393dff579
DOI: 10.1101/2023.03.01.530562

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