Article
Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy.
PloS one - 1 Jan 2017
Zheng Xiaoyi, Soroush Fariborz, Long Jin, Hall Evan T, Adishesha Puneeth K, Bhattacharya Sanchita, Kiani Mohammad F, Bhalla Vivek
Abstract excerpt
Diabetic nephropathy (DN) is the leading cause of kidney disease; however, there are no early biomarkers and no cure. Thus, there is a large unmet need to predict which individuals will develop nephropathy and to understand the molecular mechanisms that govern this susceptibility. We compared the glomerular transcriptome from mice with distinct susceptibilities to DN at four weeks after induction of diabetes, but...
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