Article

Endothelial Kallikrein-Related Peptidase 8 Promotes Diabetic Nephropathy through a LIFR dependent mechanism

2025-07-07

Abstract excerpt

<h4>Background</h4> Diabetic nephropathy (DN) is the primary microvascular complication of diabetes mellitus; however, the exact pathways in endothelial cells (ECs) linked to DN progress remain unclear. Tissue kallikrein-related peptidases (KLKs) participate in pathophysiological processes in ECs. We aimed to explore the roles of endothelial KLKs in DN and define the underlying mechanisms. <h4>Methods and results...

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Literature Corpus work: 12949456-5a61-5830-b4b5-8c3109358bfc
DOI: 10.1101/2025.07.01.662673

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