Article

Modulation of chemoattractant receptor function by C-terminus interactions

2020-01-01

Abstract excerpt

The chemokine receptors CCR3 and CCR4 play key roles in leukocyte recruitment in allergy. Consequently, both receptors are the focus of efforts to block receptor function with potential for the treatment of diseases such as asthma. Responses to chemokines are tightly regulated by the processes of receptor endocytosis and recycling. This thesis set out to examine the mechanisms by which the expression of both recep...

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Literature Corpus work: ca2abc53-1eda-57e6-baed-6c420395ae19
DOI: 10.25560/83211

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