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Article

Targeting chemokine receptors in disease – a case study of CCR4

14 May 2015

Abstract excerpt

Since their early 1990s, the chemokine receptor family of G protein-coupled receptors (GPCRs) has been the source of much pharmacological endeavour. Best known for their key roles in recruiting leukocytes to sites of infection and inflammation, the receptors present themselves as plausible drug targets for therapeutic intervention. In this article, we will focus our attention upon CC Chemokine Receptor Four...

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PMID: 25981299
DOI: 10.1016/j.ejphar.2015.05.018

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