Article

Explant Cultures From Prostate Needle Biopsies as A Model to Obtain Highly Enriched Populations of Benign and Carcinoma-Associated Fibroblasts

2021-03-01

Abstract excerpt

Prostate cancer (PCa) is a multifocal neoplasm in which different cancer foci can be found within a single organ. This feature represents a technical difficulty when obtaining highly-enriched primary cultures of human prostate stroma cells (HPSCs), since their isolation involves enzymatic digestion of large pieces of tissue, resulting in an unknown proportion of benign- (BAF) and carcinoma-associated fibroblasts (...

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Literature Corpus work: ca2281b3-35fb-5de3-a738-236c822c227e
DOI: 10.21203/rs.3.rs-181258/v1

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