Article
A distinct repertoire of cancer-associated fibroblasts is enriched in cribriform prostate cancer.
The journal of pathology. Clinical research - 1 May 2021
Hesterberg Amanda B, Rios Brenda L, Wolf Elysa M, Tubbs Colby, Wong Hong Yuen, Schaffer Kerry R, Lotan Tamara L, Giannico Giovanna A, Gordetsky Jennifer B, Hurley Paula J
Abstract excerpt
Outcomes for men with localized prostate cancer vary widely, with some men effectively managed without treatment on active surveillance, while other men rapidly progress to metastatic disease despite curative-intent therapies. One of the strongest prognostic indicators of outcome is grade groups based on the Gleason grading system. Gleason grade 4 prostate cancer with cribriform morphology is associated with...
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