Article
Primary culture and propagation of human prostate epithelial cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Niranjan Birunthi, Lawrence Mitchell G, Papargiris Melissa M, Richards Michelle G, Hussain Shirin, Frydenberg Mark, Pedersen John, Taylor Renea A, Risbridger Gail P
Abstract excerpt
Basic and translational (or preclinical) prostate cancer research has traditionally been conducted with a limited repertoire of immortalized cell lines, which have homogeneous phenotypes and have adapted to long-term tissue culture. Primary cell culture provides a model system that allows a broader spectrum of cell types from a greater number of patients to be studied, in the absence of artificially induced...
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