Article

Elevated Delta Power in a Maternal <i>UBE3A</i> -Deletion Pig Model of Angelman Syndrome

2026-02-24

Abstract excerpt

Angelman syndrome is a neurodevelopmental disorder caused by loss of the maternally inherited UBE3A allele and is characterized by severe cognitive, motor, and communication impairments. Increased delta (1– 4 Hz) activity on electroencephalogram (EEG) assessed by visual inspection and by spectral power analysis is a robust feature of the disorder in humans and rodent models and is used as a biomarker of Angelman...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ca19dd67-8086-5d7a-bd2d-bc2850cf5ed0
DOI: 10.64898/2026.02.23.707227

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Elevated Delta Power in a Maternal <i>UBE3A</i> -Deletion Pig Model of Angelman SyndromeDOI 10.64898/2026.02.23.707227Read

Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysisSemantic proximity Read

Delta power robustly predicts cognitive function in Angelman syndromeSemantic proximity Read

A preclinical pig model of Angelman syndrome mirrors the early developmental trajectory of the human conditionSemantic proximity Read

A preclinical pig model of Angelman syndrome mirrors the early developmental trajectory of the human conditionSemantic proximity Read

Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice.Semantic proximity Read

Abnormal electrophysiological phenotypes and sleep deficits in a mouse model of Angelman Syndrome.Semantic proximity Read

Early Developmental EEG and Seizure Phenotypes in a Full Gene Deletion of Ubiquitin Protein Ligase E3A Rat Model of Angelman Syndrome.Semantic proximity Read

Abnormal electrophysiological phenotypes and sleep deficits in a mouse model of Angelman SyndromeSemantic proximity Read

Neurobehavioral and electroencephalographic abnormalities in Ube3a maternal-deficient mice.Semantic proximity Read

Cell-type-specific dysregulated gene expression in the frontal cortex of an Angelman syndrome pig modelSemantic proximity Read

Longitudinal EEG model detects antisense oligonucleotide treatment effect and increased UBE3A in Angelman syndromeSemantic proximity Read

Increased aperiodic gamma power in young boys with Fragile X is associated with better language abilitySemantic proximity Read