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Article

Delta power robustly predicts cognitive function in Angelman syndrome

28 May 2021

Abstract excerpt

OBJECTIVE: Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by loss of function of the maternally inherited UBE3A gene in neurons. Promising disease-modifying treatments to reinstate UBE3A expression are under development and an early measure of treatment response is critical to their deployment in clinical trials. Increased delta power in EEG recordings, reflecting abnormal neuronal...

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PMID: 34047077
DOI: 10.1002/acn3.51385

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