Article

The ZEB1/LAYN cascade promotes cancer cell malignant phenotypes and macrophage M2 polarization in gastric cancer

2025-08-11

Abstract excerpt

<title>Abstract</title> <p> Background M2-polarized macrophages in the tumor microenvironment contribute to tumor development, angiogenesis, and immune suppression. Layilin (LAYN) is linked to macrophage infiltration and patient outcomes in gastric cancer (GC). Here, we characterized the role of LAYN in malignant progression and macrophage M2 polarization in GC. Methods Protein levels were assessed using immunob...

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Literature Corpus work: c9a540bb-e1ca-56e9-a360-5250e4174d85
DOI: 10.21203/rs.3.rs-7027452/v1

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