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AKR1B10 regulates M2 macrophage polarization to promote the malignant phenotype of gastric cancer.

Bioscience reports - 31 Oct 2023

Wu Yi, Hao Yanjie, Zhuang Qing'xin, Ma Xiaoli, Shi Chao

Abstract excerpt

BACKGROUND: Immunotherapy has brought new hope to gastric cancer (GC) patients. Exploring the immune infiltration pattern in GC and the key molecules is critical for optimizing the efficacy of immunotherapy. Aldo-keto reductase family 1 member B10 (AKR1B10) is an inflammatory regulator and is closely related to the prognosis of patients with GC. However, the function of AKR1B10 in GC remains unclear. METHODS: In...

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Identifiers

PMID: 37039038
DOI: 10.1042/BSR20222007
PMCID: PMC10545534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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