Article

Single-cell RNA sequencing and large-scale bulk combination with machine learning reveal gastric cancer-related macrophage heterogeneity

2025-10-17

Abstract excerpt

<h4>Background</h4> The tumor microenvironment (TME) significantly impacts cancer progression and overall patient survival. However, the complexity of tumor cell-TME interactions in gastric cancer (GC) and their underlying molecular basis remain to be systematically elucidated. <h4>Methods</h4> We performed single-cell RNA sequencing (scRNA-seq) on paired tumor and adjacent tissues from 3 treatment-naïve GC pati...

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Literature Corpus work: ebe8eb83-2dae-5f0c-bebc-2d2864c56591
DOI: 10.1101/2025.10.17.683046

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