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PLXDC1 serves as a potential prognostic marker and involves in malignant progression and macrophage polarization in colon cancer

12 Sept 2024

Abstract excerpt

The malignant behavior and immune escape ability of cancer cells lead to therapeutic failure and poor prognosis for patients with various cancers, including colon cancer. Plexin domain containing 1 (PLXDC1) was initially identified to exert key roles in tumor by regulating angiogenesis and has recently proved to be involved in cell proliferation and migration of glioblastoma and gastric cancer cells. However, its...

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PMID: 39267413
DOI: 10.1002/jbt.23832

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