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Molecular Imaging Insights into Neurodegeneration: Focus on Tau PET Radiotracers

15 May 2014

Abstract excerpt

Neurodegenerative diseases are characterized by progressive dysfunction and neuronal death, showing specific protein inclusions at autopsy. In vivo detection of these key proteins, namely amyloid-β, tau, α-synuclein, and trans-active response DNA-binding protein 43 kDa, is possible by means of molecular neuroimaging techniques, such as PET. The development of selective PET radiotracers targeting these proteins is...

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PMID: 24833492
DOI: 10.2967/jnumed.113.136069

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