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Examining the relationship between plasma pTau181 and cognitive decline, structural brain integrity, and biological ageing in midlife

2025-04-10

Abstract excerpt

<h4>INTRODUCTION</h4> Although plasma pTau181 has been shown to accurately discriminate patients with Alzheimer’s disease from healthy older adults, its utility as a preclinical biomarker in middle-aged community-based cohorts is unclear. <h4>METHODS</h4> Participants were members of the Dunedin Multidisciplinary Health and Development Study, a longitudinal study of 1037 people born in New Zealand in 1972-1973. Pl...

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Literature Corpus work: c9481974-6e93-5a80-8d68-dcaedf7770fb
DOI: 10.1101/2025.04.09.25325556

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