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Article

Post-transcriptional mechanisms distinguish human and chimp forebrain progenitor cells

2019-03-19

Abstract excerpt

The forebrain has expanded in size and complexity during hominoid evolution. The contribution of post-transcriptional control of gene expression to this process is unclear. Using in-depth proteomics in combination with bulk and single-cell RNA sequencing, we analyzed protein and RNA levels of almost 5,000 genes in human and chimpanzee forebrain neural progenitor cells. We found that species differences in protein...

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Literature Corpus work
c93e63f6-c80a-57db-ae53-edff55b8b83f
DOI
10.1101/582197
Open publication

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Post-transcriptional mechanisms distinguish human and chimp forebrain progenitor cellsDOI 10.1101/582197
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