Article

Simulating CD8 T Cell Exhaustion: A Comprehensive Approach

2024-09-11

Abstract excerpt

Immunotherapy has revolutionised the treatment of multiple cancer types, however, these treatments only work for a proportion of patients and biomarkers to predict response are lacking. One correlate of response is the reinvigoration of a subset of CD8 T cells that have an exhausted phenotype and impaired functionality. In order to develop new therapies, reproducible models are required to identify candidate targe...

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Literature Corpus work: c919e358-154c-5612-9fba-f13615d6a925
DOI: 10.1101/2024.09.06.611697

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