Article
Use of Mass Cytometry to Profile Human T Cell Exhaustion.
Frontiers in immunology - 1 Jan 2019
Winkler Frances, Bengsch Bertram
Abstract excerpt
Mass cytometry has become an important technique for the deep analysis of single cell protein expression required for precision systems immunology. The ability to profile more than 40 markers per cell is particularly relevant for the differentiation of cell types for which low parametric characterization has proven difficult, such as exhausted CD8+ T cells (TEX). TEX with limited effector function accumulate in...
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