Article

Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development

2017-11-21

Abstract excerpt

Transcriptomic imputation approaches offer an opportunity to test associations between disease and gene expression in otherwise inaccessible tissues, such as brain, by combining eQTL reference panels with large-scale genotype data. These genic associations could elucidate signals in complex GWAS loci and may disentangle the role of different tissues in disease development. Here, we use the largest eQTL reference p...

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Literature Corpus work: c8fb86eb-0294-5470-8172-e4632e508a23
DOI: 10.1101/222596

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