Article

Loss of circulating CD8α <sup>+</sup> NK cells during human <i>Mycobacterium tuberculosis</i> infection

2024-04-20

Abstract excerpt

Natural Killer (NK) cells can recognize and kill Mtb -infected cells in vitro, however their role after natural human exposure has not been well-studied. To identify Mtb -responsive NK cell populations, we analyzed the peripheral blood of healthy household contacts of active Tuberculosis (TB) cases and source community donors in an endemic region of Port-au-Prince, Haiti by flow cytometry. We observed higher CD8...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9f289236-74c7-54c3-80a7-c6f30eea73ee
DOI: 10.1101/2024.04.16.588542

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Loss of circulating CD8α <sup>+</sup> NK cells during human <i>Mycobacterium tuberculosis</i> infectionDOI 10.1101/2024.04.16.588542Read

NK cell phenotypic profile during active TB in people living with HIV-evolution during TB treatment and implications for bacterial clearance and disease severity.Semantic proximity Read

Peripheral blood cellular dynamics during the progression of human tuberculosisSemantic proximity Read

Enrichment of a CD4 <sup>-</sup> CD8 <sup>-</sup> NK-like cytotoxic Vδ1/3 T cell subset in tuberculosis diseaseSemantic proximity Read

Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions.Semantic proximity Read

Single-cell transcriptomics of blood reveals a natural killer cell subset depletion in tuberculosisSemantic proximity Read

Single-cell transcriptome sequencing reveals altered peripheral blood immune cells in patients with severe tuberculosisSemantic proximity Read

A genome-wide innateness gradient defines the functional state of human innate T cellsSemantic proximity Read

Airway immune signatures of protection and disease progression in recent human tuberculosis household contactsSemantic proximity Read

Assessment the Diversity of Circulating Natural Killer Cells Between Active Tuberculosis and Latent Tuberculosis InfectionSemantic proximity Read

Single-cell immune profiling at time of <i>M. tuberculosis</i> exposure reveals antigen-reactive programs that predict progression to active diseaseSemantic proximity Read

Airway immune signatures of protection and disease progression in recent human tuberculosis household contactsSemantic proximity Read

Immune profiling of <i>Mycobacterium tuberculosis</i>-specific T cells in recent and remote infectionSemantic proximity Read