Article

Embryonic Mast Cells Arise from <i>Cpa3</i> -expressing Precursors Independent of Granulocyte-Monocyte Progenitors

2024-11-02

Abstract excerpt

<h4>SUMMARY</h4> Most of the mast cells (MCs) in connective tissues, such as skin, are long-lived embryonic-derived immune cells that play important roles in host defense and various immunological diseases, including allergies. Their embryonic origin and ontogeny remain to be fully studied since several overlapping waves of embryonic hematopoiesis have been shown to give rise to these cells. Here, combining singl...

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Literature Corpus work: c8d8bfee-38ef-5d03-8203-c780129d0488
DOI: 10.1101/2024.10.30.620640

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