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Mast cell ontogeny: From fetal development to life‐long health and disease

8 Feb 2023

Abstract excerpt

Mast cells (MCs) are evolutionarily ancient innate immune cells with important roles in protective immunity against bacteria, parasites, and venomous animals. They can be found in most organs of the body, where they also contribute to normal tissue functioning, for example by engaging in crosstalk with nerves. Despite this, they are most widely known for their detrimental roles in allergy, anaphylaxis, and atopic...

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PMID: 36752151
DOI: 10.1111/imr.13191

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