Article

Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

2021-10-01

Abstract excerpt

Mast cell accumulation is a hallmark of a number of diseases including allergic asthma and systemic mastocytosis. IgE-mediated crosslinking of the FcεRI receptors causes mast cell activation and contributes to disease pathogenesis. The mast cell lineage is one of the least studied among the hematopoietic cell lineages and there are still controversies about the identity of the mast cell progenitor, i.e., whether F...

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Literature Corpus work: ad54e9b6-0cc2-5534-8c77-8d03bd820e35
DOI: 10.1101/2021.10.01.462521

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