Article
Phenotypic characterization of leukocytes in prenatal human dermis.
The Journal of investigative dermatology - 1 Nov 2012
Schuster Christopher, Vaculik Christine, Prior Marion, Fiala Christian, Mildner Michael, Eppel Wolfgang, Stingl Georg, Elbe-Bürger Adelheid
Abstract excerpt
The adult human skin harbors a variety of leukocytes providing immune surveillance and host defense, but knowledge about their ontogeny is scarce. In this study we investigated the number and phenotype of leukocytes in prenatal human skin (dermal dendritic cells (DDCs), macrophages, T cells (including FoxP3(+) regulatory T cells), and mast cells) to unravel their derivation and to get a clue as to their putative...
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