Article

Spatial transcriptomics for gene discovery identifies <i>Slc13a5</i> as a modulator of bone mechanoadaptation

2026-03-13

Abstract excerpt

Bone is a dynamic tissue that continuously adapts its structure in response to mechanical loading, an essential process for maintaining skeletal health. However, this adaptive capacity declines with aging, contributing to increased fragility and fracture risk. Developing therapeutic strategies that preserve or restore bone mechanoadaptation in patients with increased bone fragility requires identifying key molecul...

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Literature Corpus work: c8b331f9-432a-5b02-9f90-28056e61063a
DOI: 10.64898/2026.03.11.711126

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