Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease

26 Jan 2023

Abstract excerpt

Introduction Due to a lack of spatial-temporal resolution at the single cell level, the etiologies of the bone dysfunction caused by diseases such as normal aging, osteoporosis, and the metabolic bone disease associated with chronic kidney disease (CKD) remain largely unknown. Methods To this end, flow cytometry and scRNAseq were performed on long bone cells from Sost-cre/Ai9 + mice, and pure osteolineage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and osteoporosis research
Share to Bone Metabolism and Diseases
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36777346
DOI: 10.3389/fendo.2023.1063083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney diseasePMID 36777346Read ↗

Single Cell Cortical Bone Transcriptomics Defines Novel Osteolineage Gene Sets Altered in Chronic Kidney DiseaseSemantic proximity Read ↗

Dissecting the Global Dynamic Molecular Profiles of Human Fetal Kidney Development by Single-Cell RNA SequencingSemantic proximity Read ↗

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney developmentSemantic proximity Read ↗

A Landscape of Genetic and Cellular Hallmarks in Chronic Kidney DiseaseSemantic proximity Read ↗

Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associationsSemantic proximity Read ↗

Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory TargetsSemantic proximity Read ↗

Evaluation of a scalable approach to generate cell-type specific transcriptomic profiles of mesenchymal lineage cellsSemantic proximity Read ↗

Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to InjurySemantic proximity Read ↗

A systematic dissection of human primary osteoblasts <i>in vivo</i> at single-cell resolutionSemantic proximity Read ↗

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney diseaseSemantic proximity Read ↗

Spatial transcriptomic interrogation of the murine bone marrow signaling landscapeSemantic proximity Read ↗

Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.