Article

Single Cell Cortical Bone Transcriptomics Defines Novel Osteolineage Gene Sets Altered in Chronic Kidney Disease

2022-07-31

Abstract excerpt

Due to a lack of spatial-temporal resolution at the single cell level, the etiologies of the bone dysfunction caused by diseases such as normal aging, osteoporosis, and the metabolic bone disease associated with chronic kidney disease (CKD) remain largely unknown. To this end, flow cytometry and scRNAseq were performed on long bone cells from Sost-cre/Ai9 + mice, and pure osteolineage transcriptomes were identifi...

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Literature Corpus work: 44527ce7-2f3f-56a4-b5c9-55da2c6f6336
DOI: 10.1101/2022.07.30.502024

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