Article

Superovulation and aging perturb oocyte-granulosa cell communication

2023-11-01

Abstract excerpt

In vitro fertilization has been developed to overcome reduced fertility, which is increasingly due to a decline in reproductive cell quality during aging. Here, we quantitatively investigated the interplay between superovulation and aging in mouse oocytes and their paired granulosa cells using newly adapted isolation techniques. We tested the hypothesis that superovulation disrupts oocyte maturation, revealing the...

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Literature Corpus work: c8a5ca1b-5341-533f-9f87-dfd188dc567b
DOI: 10.1101/2023.10.30.563978

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