Article

Multiomics analyses reveal key circadian rhythm genes implicated in Premature ovarian insufficiency

2025-06-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Premature ovarian insufficiency (POI), defined as the loss of ovarian function before the age of 40 years, severely disrupts reproductive and endocrine health. While circadian rhythm disruption has been implicated in reproductive aging, its mechanistic contribution to POI remains largely unexplored in humans.<bold>Methods</bold> We performed an integrative multio...

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Literature Corpus work: 87775a42-fe85-5fec-b3d4-25cbfefd0cf0
DOI: 10.21203/rs.3.rs-6850329/v1

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