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Article

The effects of superovulation and reproductive aging on the epigenome of the oocyte and embryo

27 Dec 2017

Abstract excerpt

A societal preference of delaying maternal age at first childbirth has increased reliance on assisted reproductive technologies/therapies (ART) to conceive a child. Oocytes that have undergone physiologic aging (≥35 years for humans) are now commonly used for ART, yet evidence is building that suboptimal reproductive environments associated with aging negatively affect oocyte competence and embryo...

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PMID: 29280527
DOI: 10.1002/mrd.22951

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