Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal muscle

27 Feb 2020

Abstract excerpt

Macrophages are characterized by a high plasticity in response to changes in tissue microenvironment, which allows them to acquire different phenotypes and to exert essential functions in complex processes, such as tissue regeneration. Here, we report that the membrane protein Cripto plays a key role in shaping macrophage plasticity in skeletal muscle during regeneration and disease. Conditional deletion of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GDF15 and Related Biomarkers
Share to Immune cells in cancer
Share to Muscle Physiology and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32107853
DOI: 10.15252/embr.201949075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal musclePMID 32107853Read ↗

Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and DiseasesSemantic proximity Read ↗

Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle RepairSemantic proximity Read ↗

Phenotypic transitions of macrophages orchestrate tissue repair.Semantic proximity Read ↗

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosisSemantic proximity Read ↗

Macrophages upregulate mural cell-like markers and support healing of ischemic injury by adopting functions important for vascular support.Semantic proximity Read ↗

Pro-inflammatory macrophages impair skeletal muscle regeneration in ischemic-damaged limbs by inducing precocious differentiation of satellite cellsSemantic proximity Read ↗

Macrophages support healing of ischemic injury by transdifferentiating towards mural cells and adopting functions important for vascular supportSemantic proximity Read ↗

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophySemantic proximity Read ↗

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosisSemantic proximity Read ↗

Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architectureSemantic proximity Read ↗

Macrophages: Redefining extracellular matrix architecture through phenotypic switches as therapeutic targets.Semantic proximity Read ↗

Macrophages in Tissue Repair, Regeneration, and Fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.