Article
Macrophages in Tissue Repair, Regeneration, and Fibrosis.
Immunity - 15 Mar 2016
Wynn Thomas A, Vannella Kevin M
Abstract excerpt
Inflammatory monocytes and tissue-resident macrophages are key regulators of tissue repair, regeneration, and fibrosis. After tissue injury, monocytes and macrophages undergo marked phenotypic and functional changes to play critical roles during the initiation, maintenance, and resolution phases of tissue repair. Disturbances in macrophage function can lead to aberrant repair, such that uncontrolled production of...
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