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Article

Single-cell transcriptomics predicts relapse in <i>MLL</i>-rearranged acute lymphoblastic leukemia in infants

2020-04-17

Abstract excerpt

Infants with MLL -rearranged acute lymphoblastic leukemia (ALL) undergo intense therapy to counter a highly aggressive leukemia with survival rates of only 30-40%. The majority of patients initially show therapy response, but in two-thirds of cases the leukemia returns, typically during treatment. Accurate relapse prediction would enable treatment strategies that take relapse risk into account, with potential bene...

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Literature Corpus work
c8391fb5-a09e-5af6-91c1-a8f6d32fbad1
DOI
10.1101/2020.04.14.20056580
Open publication

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Single-cell transcriptomics predicts relapse in <i>MLL</i>-rearranged acute lymphoblastic leukemia in infantsDOI 10.1101/2020.04.14.20056580
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