Article

Associations of Polygenic Scores and Developmental Trajectories of Externalizing Behaviors

2024-04-24

Abstract excerpt

<p>Polygenic scores (PGSs) have garnered increasing attention in the clinical sciences due to their robust prediction signals for psychopathology, including externalizing (EXT) behaviors. However, studies leveraging PGS approaches have rarely accounted for the phenotypic and developmental heterogeneity in EXT outcomes. Additionally, many genetically informed studies of EXT tend to exclude non-European ancestry gro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c7bb6860-69e1-54ef-82bc-90d1befadebe
DOI: 10.31234/osf.io/36vfa

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Associations of Polygenic Scores and Developmental Trajectories of Externalizing BehaviorsDOI 10.31234/osf.io/36vfaRead

Multi-polygenic scores for externalizing behavior in schoolchildrenSemantic proximity Read

Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples.Semantic proximity Read

A multivariate approach to understanding the genetic overlap between externalizing phenotypes and substance use disorders.Semantic proximity Read

Polygenic Scores Predict the Development of Alcohol and Nicotine Use Problems from Adolescence through Young AdulthoodSemantic proximity Read

Associations Between a Genetic Liability Toward Externalizing and Behavioral Outcomes Spanning Toddlerhood Through Early Adulthood in Five Developmental Cohorts.Semantic proximity Read

Associations of childhood adversity and substance use disorder polygenic scores with disorder severity and diagnostic criteria.Semantic proximity Read

Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance UseSemantic proximity Read

A Family-Based Genome Wide Association Study of Externalizing Behaviors.Semantic proximity Read

Polygenic Risk for Substance-Related Traits Predicts Substance Use Onset and Progression: Sex and Population Group DifferencesSemantic proximity Read

Trajectories of genetic risk across dimensions of alcohol use behaviors.Semantic proximity Read

Parsing Genetically Influenced Risk Pathways: Genetic Loci Impact Problematic Alcohol Use Via Externalizing and Specific RiskSemantic proximity Read

Clinical, Environmental, and Genetic Risk Factors for Substance Use Disorders: Characterizing Combined Effects across Multiple CohortsSemantic proximity Read