Article

Multi-polygenic scores for externalizing behavior in schoolchildren

2025-12-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Externalizing behavior refers to emotional and behavioral problems or disorders characterized by conducts directed outward at an individual’s environment. Polygenic scores (PGSs) indexing the individual genetic susceptibility for this behavior still explain a small proportion of the phenotypic variance. To increase this phenotypic variance explained for externalizing behavio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0d214f2a-f03f-527f-acf8-d78a36a1757c
DOI: 10.64898/2025.12.19.25342558

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-polygenic scores for externalizing behavior in schoolchildrenDOI 10.64898/2025.12.19.25342558Read

Genetics of educational attainment and social problem behaviors: Robust estimates of direct genetic effectsSemantic proximity Read

Associations Between a Genetic Liability Toward Externalizing and Behavioral Outcomes Spanning Toddlerhood Through Early Adulthood in Five Developmental Cohorts.Semantic proximity Read

Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhoodSemantic proximity Read

The Genetics of Externalizing Problems.Semantic proximity Read

Associations of Polygenic Scores and Developmental Trajectories of Externalizing BehaviorsSemantic proximity Read

Gene-environment interplay in externalizing behavior from childhood through adulthood.Semantic proximity Read

Maternal environmental risk factors and the development of internalizing and externalizing problems in childhood: The complex role of genetic factorsSemantic proximity Read

Genetic Liability for Internalizing–Externalizing Traits in Mexican Youth: Moderation by AdversitySemantic proximity Read

Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes.Semantic proximity Read

Unique and shared internalizing and externalizing genetic factors associated with suicidal thoughts and behaviors: Findings from the adolescent brain cognitive development study.Semantic proximity Read

Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance UseSemantic proximity Read

A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology SpectraSemantic proximity Read