Article

An antigenic diversification threshold for falciparum malaria transmission at high endemicity

2020-01-02

Abstract excerpt

In malaria and several other important infectious diseases, high prevalence occurs concomitantly with incomplete immunity. This apparent paradox poses major challenges to malaria elimination in highly endemic regions, where asymptomatic Plasmodium falciparum infections are present across all age classes creating a large reservoir that maintains transmission. This reservoir is in turn enabled by extreme antigenic...

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Literature Corpus work: c75efe19-48c7-53f4-9bcb-9888663f10c2
DOI: 10.1101/2020.01.01.892406

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