Article

Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in <i>Plasmodium falciparum</i>

2018-09-03

Abstract excerpt

In their competition for hosts, parasites with antigens that are novel to host immunity will be at a competitive advantage. The resulting frequency-dependent selection can structure parasite populations into strains of limited genetic overlap. For Plasmodium falciparum –the causative agent of malaria–in endemic regions, the high recombination rates and associated vast diversity of its highly antigenic and multico...

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Literature Corpus work: 955b759e-2ff8-5e4d-926d-a05fe3990478
DOI: 10.1101/406546

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