Article
Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.
PLoS pathogens - 1 Mar 2011
Recker Mario, Buckee Caroline O, Serazin Andrew, Kyes Sue, Pinches Robert, Christodoulou Zóe, Springer Amy L, Gupta Sunetra, Newbold Chris I
Abstract excerpt
Many pathogenic bacteria, fungi, and protozoa achieve chronic infection through an immune evasion strategy known as antigenic variation. In the human malaria parasite Plasmodium falciparum, this involves transcriptional switching among members of the var gene family, causing parasites with differ...
Topics
- Algorithms
- Antigenic Variation
- Antigens, Protozoan
- Gene Expression Profiling
- Malaria, Falciparum
- Phenotype
- Plasmodium falciparum
- Protozoan Proteins
- Transcription, Genetic