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Article

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.

PLoS pathogens - 1 Mar 2011

Recker Mario, Buckee Caroline O, Serazin Andrew, Kyes Sue, Pinches Robert, Christodoulou Zóe, Springer Amy L, Gupta Sunetra, Newbold Chris I

Abstract excerpt

Many pathogenic bacteria, fungi, and protozoa achieve chronic infection through an immune evasion strategy known as antigenic variation. In the human malaria parasite Plasmodium falciparum, this involves transcriptional switching among members of the var gene family, causing parasites with different antigenic and phenotypic characteristics to appear at different times within a population. Here we use a...

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Identifiers

PMID: 21408201
DOI: 10.1371/journal.ppat.1001306
PMCID: PMC3048365

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Source receipt: pubmed, retrieved 7 Sept 2026.

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