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Article

An immune memory-structured SIS epidemiological model for hyperdiverse pathogens.

Proceedings of the National Academy of Sciences of the United States of America - 7 Nov 2023

de Roos André M, He Qixin, Pascual Mercedes

Abstract excerpt

A hyperdiverse class of pathogens of humans and wildlife, including the malaria parasite Plasmodium falciparum, relies on multigene families to encode antigenic variation. As a result, high (asymptomatic) prevalence is observed despite high immunity in local populations under high-transmission settings. The vast diversity of "strains" and genes encoding this variation challenges the application of established...

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Identifiers

PMID: 37910552
DOI: 10.1073/pnas.2218499120
PMCID: PMC10636369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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