Article

Hyper-diverse antigenic variation and resilience to transmission-reducing intervention in falciparum malaria

2024-02-05

Abstract excerpt

Intervention against falciparum malaria in high transmission regions remains challenging, with relaxation of control efforts typically followed by rapid resurgence. Resilience to intervention co-occurs with incomplete immunity, whereby children eventually become protected from severe disease but not infection and a large transmission reservoir results from high asymptomatic prevalence across all ages. Incomplete i...

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Literature Corpus work: be7626f2-ea28-57ad-8ba1-5ff11cfc294a
DOI: 10.1101/2024.02.01.24301818

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