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Article

CalMaTe: a method and software to improve allele-specific copy number of SNP arrays for downstream segmentation.

Bioinformatics (Oxford, England) - 1 Jul 2012

Ortiz-Estevez Maria, Aramburu Ander, Bengtsson Henrik, Neuvial Pierre, Rubio Angel

Abstract excerpt

SUMMARY: CalMaTe calibrates preprocessed allele-specific copy number estimates (ASCNs) from DNA microarrays by controlling for single-nucleotide polymorphism-specific allelic crosstalk. The resulting ASCNs are on average more accurate, which increases the power of segmentation methods for detecting changes between copy number states in tumor studies including copy neutral loss of heterozygosity. CalMaTe applies...

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PMID: 22576175
DOI: 10.1093/bioinformatics/bts248
PMCID: PMC3381965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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