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Article

Precise inference of copy number alterations in tumor samples from SNP arrays.

Bioinformatics (Oxford, England) - 1 Dec 2013

Chen Gary K, Chang Xiao, Curtis Christina, Wang Kai

Abstract excerpt

MOTIVATION: The accurate detection of copy number alterations (CNAs) in human genomes is important for understanding susceptibility to cancer and mechanisms of tumor progression. CNA detection in tumors from single nucleotide polymorphism (SNP) genotyping arrays is a challenging problem due to phenomena such as aneuploidy, stromal contamination, genomic waves and intra-tumor heterogeneity, issues that leading...

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Identifiers

PMID: 24021380
DOI: 10.1093/bioinformatics/btt521
PMCID: PMC3834792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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