Article

Human endogenous retroviruses are upregulated in Frontotemporal Dementia-MAPT mutation carriers

2024-01-17

Abstract excerpt

<title>Abstract</title> <p>Previous studies have identified an upregulation of human endogenous retroviruses (HERVs) in several disorders, but little is known about their role in neurodegenerative dementias. In this study, we investigate a possible role of HERVs in the pathogenesis of sporadic and genetic frontotemporal dementia (FTD) and Alzheimer’s disease (AD). We measured HERVs transcripts using quantitative...

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Literature Corpus work: c6e22f8b-6358-569f-a210-43ca08ad6a86
DOI: 10.21203/rs.3.rs-3848745/v1

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