Article

Mobile DNA Activity in Parkinson’s Disease: A Locus-Specific View of Endogenous Retroviruses

2026-07-03

Abstract excerpt

Human endogenous retroviruses (HERVs) are mobile genetic sequences derived from ancient retroviral infections. While typically silenced, their reactivation has been implicated in gene dysregulation, aging, and immune-related transcriptional pathogenesis of some neurodegenerative diseases. Parkinson’s disease (PD) is the second most common neurodegenerative disorder, yet its etiology and HERV reactivation remain po...

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Literature Corpus work: 76a161ff-c6ee-5c37-b766-ca2b9753b746
DOI: 10.64898/2026.07.03.736370

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