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Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease

26 Jul 2019

Abstract excerpt

Transposable Elements (TEs) are mobile genetic elements whose sequences constitute nearly half of the human genome. Each TE copy can be present in hundreds to thousands of locations within the genome, complicating the genetic and genomic studies of these highly repetitive sequences. The recent development of better tools for evaluating TE derived sequences in genomic studies has enabled an increasing appreciation...

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PMID: 31372185
DOI: 10.1186/s13100-019-0176-1

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